Owner-Intruder Contests with Information Asymmetry

Owner-Intruder Contests with Information Asymmetry Faheem Farooq, Depts. of Biology and Chemistry, Jay Bisen, Manaeil Hasan, and Akhil Patel, with Dr. Jan Rychtar, Dept. of Mathematics and Discrete Mathematics, and Dr. Dewey T. Taylor, Dept. of Mathematics and Discrete Mathematics We consider kleptoparasitic interactions between two individuals - Owner and Intruder - and model the situation as a sequential game in an extensive form. Owner is in a possession of a valuable resource when it spots Intruder. Owner has to decide whether to defend the resource; if the Owner defends, the Intruder has to decide whether to fight with the Owner. The individuals may value the resource differently and we distinguish three information cases: (a) both individuals know resource values to both of them, (b) individuals know only their own valuation, (c) individuals do not know the value at all. We solve the game in all three cases. We find that it is typically beneficial for the individuals to know as much information as possible. However, we identify several scenarios where knowing less seems better. We also show that an individual may or may not benefit from their opponent knowing less. Finally, we consider the same kind of interactions but with the reversed order of decisions. We find that typically the individual initiating the interaction has an advantage. However, when individuals know only their own valuation and not the valuations to their opponents, it is sometimes better when the opponent initiates.https://scholarscompass.vcu.edu/uresposters/1298/thumbnail.jp

Prognosis of Severe Covid-19 patients after treatment with Therapeutic Plasma Exchange (TPE)

OBJECTIVE: To demonstrate the effective role of plasmapheresis in the treatment of Cytokine Release Syndrome associated with severe Covid 19 pneumonia. INTRODUCTION: Covid-19 disease is a deadly contagious disease with milder symptoms to a more severe form with acute respiratory failure, septic shock leading to even death. Literature study showed  that  in severe  Covid-19  patients, a hyper-inflammatory response  to  initial  infection could accelerate  to  severe  hyper-cytokinaemia that  could  lead to  an  underlying endothelial  dysfunction and multiple organ dysfunction. Thus, removal of these inflammatory cytokines by Therapeutic Plasma Exchange is considered to be an essential part of the treatment of critically ill patients in order to improve their survival rates. METHODOLOGY:  Retrospective observational study which included 150 RT-PCR positive patients admitted in Covid ITC, from the time period of 1st February 2021 to 31st July 2021 –removed for blind review---Data was analyzed using SPSS software version 16. Frequencies were calculated along with mean and standard deviation. Chi square and ANOVA test was applied to the data. P value <0.05 was considered statistically significant. Linear regression study was applied to predict the prognosis. RESULTS: Out of 150 patients, 51 patients (34%) were of severe ARDS category of whom 13 (25.5%) developed Cytokine Release Syndrome. They received plasmapheresis therapy subsequently and 7 out of those 13 (53.8%) patients got improved. P- value was found to be significant ( <0.05). Overall, the mortality rate was low with 120/150 (80%) getting discharged successfully. CONCLUSION:  Our findings suggest that Therapeutic plasma exchange is beneficial in Cytokine storm caused by SARS-CoV2 removing the inflammatory cytokines and improving symptoms, thereby, avoiding intubation. KEY WORDS: , Therapeutic plasma exchange, Hypercytokinaemia, Cytokine Release Syndrom

Role of Dexmedetomidine by Improving Sleep Quality and Pain Control in Covid-19 Patients

OBJECTIVE: To demonstrate the effective role of Dexmedetomidine as a sedative and analgesic agent in Covid-19 patients when used in conjunction with the established treatment of Acute Respiratory Distress Syndrome.  INTRODUCTION: Covid-19 disease is a deadly contagious disease with milder symptoms to a more severe form with acute respiratory failure, septic shock leading to even death. Literature study shows High Flow Nasal Oxygen therapy and prolonged prone position sessions to be beneficial in the treatment of ARDS, however, to facilitate those sessions, a sedative and anxiolytic agent must be added in the treatment. Therefore, this study was conducted to document the beneficial role of dexmedetomidine as a sedative agent.  METHODOLOGY: Retrospective observational study which included 150 PCR positive patients admitted in Covid ITC, from 1st February 2021 to 31st July 2021 residing in the premises of PAF Air Base, Mushaf, Sargodha. Data was analyzed using SPSS software.   RESULTS: Out of 150 patients, 120 (80%) were treated with High Flow Nasal Oxygen (HFNO), Dexmedetomidine infusion (DEXME) and long periods of prone position (PP) sessions. Among these 120 patients, 88 (73.3%) were discharged while 32 (26.67%) patients died of which 7 (21.875%) died while being on HFNO therapy and 25 (78.125%) patients were intubated. DEXME infusion was found to have a positive outcome (P-value <0.005) in the treatment of moderate to severe ARDS.  CONCLUSION: Our findings suggest that DEXME infusion is beneficial in moderate to severe ARDS caused by SARS-CoV2  when given along with HFNO therapy and prolonged PP sessions, thereby, avoiding intubation. 

Do migrant remittances spur financial development in Pakistan? evidence from linear and nonlinear ARDL approach

The study asseses the influence of migrant remittances on financial development over the period of 1976-2018 in Pakistan. This study has applied the linear autoregressive distributive lag (ARDL) model and nonlinear autoregressie distributed lag (NARDL) model to check the symmetric and asymmetric effect of remittances. Results of the ARDL and NARDL bound test confirm remittances, FDI, real GDP and inflation significantly contributing to financial development. The outcomes of ARDL and NARDL have also confirmed the significant positive effect of migrant remittances on financial development in long-run. The asymmetric ARDL results show the existence of remittances nonlinear effect on financial development. Specifically, the study found remittances decrease have a significant impact while remittances increase have no any significant effect on financial development. Based on findings, this study recommends the plan for the policymakers of recipient countries, especially Pakistan, could harvest the potential gain of migrant remittances though positive asymmetric association with financial sector development

A Novel Control Approach to Hybrid Multilevel Inverter for High-Power Applications

This paper proposes a hybrid control scheme for a newly devised hybrid multilevel inverter (HMLI) topology. The circuit configuration of HMLI is comprised of a cascaded converter module (CCM), connected in series with an H-bridge converter. Initially, a finite set model predictive control (FS-MPC) is adopted as a control scheme, and theoretical analysis is carried out in MATLAB/Simulink. Later, in the real-time implementation of the HMLI topology, a hybrid control scheme which is a variant of the FS-MPC method has been proposed. The proposed control method is computationally efficient and therefore has been employed to the HMLI topology to mitigate the high-frequency switching limitation of the conventional MPC. Moreover, a comparative analysis is carried to illustrate the advantages of the proposed work that includes low switching losses, higher efficiency, and improved total harmonic distortion (THD) in output current. The inverter topology and stability of the proposed control method have been validated through simulation results in MATLAB/Simulink environment. Experimental results via low-voltage laboratory prototype have been added and compared to realize the study in practice.publishedVersio

Locking Versus Non-Locking Miniplates in the Treatment of Mandibular Fractures in Above 35 Years Age Patients

Objective: To compare the frequency of short term post-operative infection of locking plates versus non-locking plate in mandibular fractures in patients above 35 years of age. Methodology: A randomized controlled study was conducted at the Department of Oral and Maxillofacial Surgery, Pakistan Institute of Medical Sciences, Islamabad from January 2018 to January 2019, involving a 100 patients (50 patients in each group). On the basis of history, clinical features, orthopantomogram (OPG) and intraoperative findings, the diagnosis of mandibular fractures was established. Group A patients were treated with reduction and fixation of fracture with locking miniplates and miniscrews following champy’s principle of osteosynthesis. Whereas in group B patients, fractures were reduced and fixed with non-locking miniplates and miniscrews following champy’s principle of osteosynthesis. Results: Effect modifiers such as age, gender, and type of fracture were controlled by stratification. A post-stratification chi-square test was applied. The 1 patient that had infection in group A had an age range 50- 65 years (53 years) (P value: 0.197) while the 2 patients that had infection in group B were younger in age range of 35-50 years (36 years and 38 years) (P value: 0.322). The 1 patient who had infection in group A was female (P value: 0.043) while the 2 patients of group B who had infection were also females (P value: 0.027). In group A, only 1 patient had infection at the para-symphysis of mandible according to site (P value: 0.494). In group B, 1 patient had infection at para-symphysis of mandible and 1 at the body of the mandible site (P value: 0.599).  The results were not statistically significant in terms of infection by the end of 3rd week. Conclusion: The study concludes that insignificant post-operative infection rates while managing mandibular fractures either by locking plates or non-locking plates.

Tuberculosis: an experience at government chest disease hospital

Background: This retrospective study was carried out to find the incidence, clinical profiles and treatment outcome of pulmonary and extrapulmonary tuberculosis patients attending the only Chest Disease Hospital in Srinagar.Methods: A retrospective analysis of 613 patients having EPTB and PTB was undertaken from the chest disease hospital of Government Medical College Srinagar. Demographic characteristics, clinical features and treatment outcome were obtained from medical case records of all patients visiting the hospital for a period of two years from May 2016-May 2018.Results: The study comprised of 613 patients, out of which 365% were having pulmonary TB while 35% were having extrapulmonary TB. Majority of patients (44.5%) in TB group were in age group 10-30 while majority of patients (42%) in EPTB group were in age group 51-70. Males were seen more commonly affected. Majority (90%) of patients in EPTB group had pleural effusion. Majority of patients (71%) were smear positive by ZN staining in PTB group. Majority (90%) of PTB patients in smear negative group were BAL negative. In PTB group 8% were treatment failure while in EPTB group 2% were treatment failure. MDR was seen in 4.2% of total tuberculosis patient while XDR was seen in 0.32% of total patients. Out of treatment failure in PTB group MDR was seen in 64% followed by monoresistance to INH in 30% and XDR in 6%. In EPTB group MDR was seen in 100% of treatment failure. All patients with XDR died. Among the MDR patients majority are on treatment while 12% died, another 12% defaulter while 12% completed treatment.Conclusions: Among evaluated tuberculosis patients, maximum had PTB. Pleural tuberculosis was the most common presentation of EPTB. The study shows male preponderance in both groups. Treatment response was excellent with failure rate of 8% in PTB and 2% in EPTB. Most common cause of failure was MDR. XDR was seen in two patients and both of them died

A stable TiO2_{2}–graphene nanocomposite anode with high rate capability for lithium-ion batteries

A rapid microwave hydrothermal process is adopted for the synthesis of titanium dioxide and reduced graphene oxide nanocomposites as high-performance anode materials for Li-ion batteries. With the assistance of hydrazine hydrate as a reducing agent, graphene oxide was reduced while TiO$_{2}$ nanoparticles were grown in situ on the nanosheets to obtain the nanocomposite material. The morphology of the nanocomposite obtained consisted of TiO$_{2}$ particles with a size of ∼100 nm, uniformly distributed on the reduced graphene oxide nanosheets. The as-prepared TiO$_{2}$–graphene nanocomposite was able to deliver a capacity of 250 mA h g−1 ± 5% at 0.2C for more than 200 cycles with remarkably stable cycle life during the Li+ insertion/extraction process. In terms of high rate capability performance, the nanocomposite delivered discharge capacity of ca. 100 mA h g−1 with >99% coulombic efficiency at C-rates of up to 20C. The enhanced electrochemical performance of the material in terms of high rate capability and cycling stability indicates that the as-developed TiO$_{2}$–rGO nanocomposites are promising electrode materials for future Li-ion batteries

Formal sector price discoveries: preliminary results from a developing country

We present preliminary results of 1086 structured interviews about price setting behavior of the formal firms in the manufacturing and services sector of Pakistan. Our key discoveries are that frequency of price change is considerably high in Pakistan, lowering the real impact of monetary policy. Price rigidity is explained mainly by firms caring about relative prices and the persistence of a given shock. The exchange rate and cost shocks are more important than financial and demand shocks for both setting prices and also the readiness with which these pass-through to the economy. Large firms change prices more frequently compared to smaller firms. Formal sector firms, especially medium sized firms, interact more with informal sector firms through the demand and supply channels. Formal firms highly connected with the informal sector have lower frequency of price changes. Formal sector firms hold lack of taxes and compliance with tax regime, i.e. enforcement, as the main reasons for the existence of the informal sector